Every third Thursday of the month, this massive hub for all-cool-things-related-to-science hosts guests enjoying science-themed cocktail concoctions and plates of food from local vendors ($5), during a neon-lit, 21-and-over dance party with a monthly costume theme (February's is Mardi Gras). Interactive exhibits, including a workshop on electromagnetic fields where guests can experience the Faraday cage, are included with admission. The largest planetarium in the Western Hemisphere and premium exhibit "Star Trek: The Starfleet Academy Experience" are accessible at extra cost. | Liberty Science Center, 222 Jersey City Blvd., entrance at Phillip St., Jersey City, New Jersey, 201.200.1000
This lounge—with graffiti-painted booths, a full dinner menu and no drink minimum—is hidden on the fourth floor of a sleek, modern hotel, where cabaret performances (e.g., The Skivvies), big band jazz-sets, musicals and solo artists fill out the venue's eclectic calendar. Tony award-winner Lillias White performs "Baby-Makin' Music" on Valentine's Day, in celebration of the entertainment hall's first birthday. | YOTEL New York, 570 10th Ave., 646.449.7792.
This NYC club-scene—an elegant Italian restaurant by day and evening; a luxe, subterannean dancery by night and early morning—mirrors its Las Vegas location, the nightlife brand's original outpost, with plush red banquettes, leather sofas, dazzling disco balls and a chandelier spotlighting a team of mixology masters and their arsenal of libations. World-class DJs visiting the Upper East Side's socialite sanctuary this month include Bingo Players (Feb. 3), Chuckie (Feb. 8) and Ferry Corsten (Feb. 17). | 39 E. 58th St., 212.750.5588